Venlafaxine hydrochloride is antidepressant which belongs to class of antidepressants called serotonin-norepinephrine reuptake inhibitors (SNRI). Venlafaxine is marketed under the tradenames Effexor in the UK, Efexor, Efectin, Effexor XR and Efectin ER. Venlafaxine is used primarily for the treatment of depression, generalized anxiety disorder, social anxiety disorder, and panic disorder in adults.

Many doctors are starting to prescribe venlafaxine "off label" for the treatment of diabetic neuropathy (in a similar manner to duloxetine) and migraine prophylaxis (in some people, however, venlafaxine can exacerbate or cause migraines). Studies has shown venlafaxines effectiveness for these conditions. It has also been found to reduce the severity of 'hot-flashes' in menopausal women.

Substantial weight loss in patients with major depression, generalized anxiety disorder, and social phobia has been noted, but the manufacturer does not recommend use as an anorectic either alone or in combination with phentermine or other amphetamine-like drugs.

Venlafaxine is an effective anti-depressant for many persons; however, it seems to be especially effective for those with treatment-resistant depression. Some of these persons have taken two or more antidepressants prior to venlafaxine with no relief. Patients suffering with severe long-term depression typically respond better to venlafaxine than other drugs. However, venlafaxine has been reported to be more difficult to discontinue than other anti-depressants. However, this should not be considered a definitive finding, since responses to psychiatric medications can vary significantly from individual to individual.

Prescribed dosages are typically in the range of 75 to 225 mg per day, but higher dosages are sometimes used for the treatment of severe or treatment-resistant depression. Because of its relatively short half-life of 5 hours, venlafaxine should be administered in divided dosages throughout the day.

Before taking any prescription medicine, it is important that you consult your doctor!