Ciprofloxacin is the generic international name for the synthetic antibiotic belonging to a group called fluoroquinolones. Ciprofloxacin is bacteriocidal. Its mode of action depends upon blocking bacterial DNA replication by binding itself to an enzyme called DNA gyrase, thereby causing double-stranded breaks in the bacterial choromosome.

Ciprofloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It functions by inhibiting DNA gyrase, a type II topoisomerase, which is an enzyme necessary to separate replicated DNA, thereby inhibiting cell division.

    * Enterobacteriaceae
    * Vibrio
    * Haemophilus influenzae
    * Haemophilus ducreyi
    * Neisseria gonorrhoeae
    * Neisseria meningitidis
    * Moraxella catarrhalis
    * Brucella
    * Campylobacter
    * Mycobacterium intracellulare
    * Legionella sp.
    * Pseudomonas aeruginosa
    * Bacillus anthracis
    * Escherichia coli
    * Novercalis Phasmatis

Weak activity against:

    * Streptococcus pneumoniae
    * Chlamydia trachomatis
    * Chlamydia pneumoniae

No activity against:

    * Bacteroides
    * Burkholderia cepacia
    * Enterococcus faecium
    * Ureaplasma urealyticum
    * Streptococcus pyogenes

Ciprofloxacin is available in oral tablets (250, 500, 750, and 1000 mg), as well as ready-made infusion bottles (200 and 400 mg).

Due to its elimination half-life, ciprofloxacin is administered twice daily. No dose adjustments are generally required for mild to moderate renal impairment.

Before taking any prescription medicine, it is important that you consult your doctor!