Co-amoxiclav (Augmentin Duo) is combination antibiotic containing Amoxicillin (as either trihydate or the sodium salt) and Clavulanic acid (as Potassium clavulanate). The combination of amoxicillin, a beta-lactam antibiotic; with clavulanic acid, a beta-lactamase inhibitor; results in an antibiotic with an increased spectrum of action and restored efficacy against beta-lactamase producing amoxicillin-resistant bacteria.

Standard adult dosages for respiratory tract, urinary, abdominal and dental infections as well as cellulitis and animal bites is co-amoxiclav 250/125 (one tablet Augmentin 250) taken every 8 hours, which may be doubled in severe infections (either as two tablets at a time of Augmentin 250, or a single tablet of co-amoxiclav 500/125 ≡ Augmentin 500).

Dosages for children are also given three times a day using suspensions containing co-amoxiclav 250/62 in each 5 mL (Augmentin '250/62 SF') for those between the ages of 6 - 12 years and co-amoxiclav 125/31 (Augmentin '125/31 SF') for those between the ages of 1 - 6 years. A more concentrated solution, co-amoxiclav 400/57 (Augmentin '400/57 SF'), may be administered more conveniently just twice daily to children from as young as 2 months of age; quantities are based on body weight with 2.5 mL from the age of 2 years and 5 mL after the age of 6 years.

Amongst the possible side-effects of this medication are diarrhea, vomiting and a few other conditions. These do not usually require medical attention. However, if the patient experiences an allergic reaction to the medication, jaundice, fever or severe diarrhea, it is necessary to contact a doctor immediately. As with all antimicrobial agents, pseudomembranous colitis has been associated with the use of amoxicillin-clavulanate. Amoxicillin is a member of the penicillin family of antibiotics, and therefore should not be taken by patients allergic to penicillin.

Before taking any prescription medicine, it is important that you consult your doctor!