Description
Brand name: VegaH long energising cream for man Active substance: Sildenafil citrate 2%, lignocaine (lidocaine) 2% Packaging: tube with 15 gr of gel (water soluble) Shipped from: India
VegaH cream prolongs erection and ejaculation in man. Active substance Sildenafil (Viagra) prolongs erection by inhibiting PDE5 enzymes while lignocaine has local anesthetic properties which can decrease sensitivity of penis and prolong ejaculation. Apply a small amount to head and shaft of penis before intercourse, or use as directed by physician. Do not use this product in combination with additional Viagra, Cialis or Levitra.
Detailed sildenafil explanation
Sildenafil citrate, sold under the names Viagra, Revatio, Vectra and
(in the Indian subcontinent) Caverta, is a drug used to treat male
erectile dysfunction (impotence) and pulmonary arterial hypertension
(PAH), developed by the pharmaceutical company Pfizer.
Part of the physiological process of erection involves the
parasympathetic nervous sytem to release nitric oxide (NO) in the
corpus cavernosum of the penis. NO binds to the receptors of the enzyme
guanylate cyclase which results in increased levels of cyclic guanosine
monophosphate (cGMP), leading to smooth muscle relaxation
(vasodilation) in the corpus cavernosum, resulting in increased inflow
of blood and an erection.
Sildenafil is a potent and selective inhibitor of cGMP specific
phosphodiesterase type 5 (PDE5) which is responsible for degradation of
cGMP in the corpus cavernosum. The molecular structure of sildenafil is
similar to that of cGMP and acts as a competitive binding agent of cGMP
in the corpus cavernosum, resulting in better erections. Without sexual
stimulation and no activation of the NO/cGMP system, sildenafil should
not cause an erection. Other drugs that operate by the same mechanism
include tadalafil (Cialis?) and vardenafil (Levitra?).
Sildenafil is metabolised by hepatic enzymes and excreted by both
the liver and kidneys. If taken with a high fat meal, there may be a
delay in absorption of sildenafil and the net effect might be muted
slightly as the plasma concentration will be lowered. Some reports have
claimed that sildenafil causes enhanced sexual pleasure for women by
increasing blood flow to the sexual organs. Before taking any prescription medicine, it is important that you consult your doctor!
|